Sessions

Integrated TK-TD modeling for Aconitum kusnezoffii and compatibility of Terminalia chebula in Mongolian

[Speaker] Xin Miao:1
[Co-author] Dan Dan Liu:1, Xing Zi Ma:1, Gang Li:1
1:Inner Mongolia Medical University Inner Mongolia Hohhot City China, China

Paeoniflorin reduced cardiotoxicity of aconitine in H9c2 Cells

[Speaker] Shuhan Zhang:1
[Co-author] Dan He:1, Jiangfeng Wang:1, Jinqi Li:1,2,3
1:School of medicine, University of Electronic Science and Technology of China, Chengdu, China, 2:Sichuan Academy o Medical Sciences & Sichuan Provincial People's Hospital, Chengdu, China, 3:Sichuan Key Laboratory for individualized drug therapy, Chengdu, China

A Bone Histomorphometric Study in Mice with Antiepileptics, Perampanel and Phenytoin

[Speaker] Kenji Onodera:1
[Co-author] Taisuke Otsuki:2, Takashi Soga:2, Junkichi Kanda:3, Hiroyuki Wakabayashi:3
1:Department of Clinical Pharmacotherapy and Pharmacy, Bethel Epilepsy Centre, Japan, 2:Bethel Epilepsy Centre, Japan, 3:Department of Clinical Pharmacotherapy, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences, Japan

Characterization of response to acute and chronic arsenic toxicity in CD34high-enriched epidermal stem cells

[Speaker] Yuanyuan Xu:1
[Co-author] Yuxin Hu:1, Xiafang Wu:1, Ru Sun:1, Xin Fang:1, Huihui Wang:1, Jingbo Pi:1
1:School of Public Health, China Medical University, China

Effect of the heat-not-burn tobacco-extracted substances on the brain endothelial barrier function in vitro

[Speaker] Ikuya Kimura:1
[Co-author] Shinya Dohgu:1, Fuyuko Takata:1, Junichi Matsumoto:1, Mai Rikitake:1, Atsushi Yamauchi:1, Yasufumi Kataoka:1
1:Department of Pharmaceutical Care and Health Sciences, Faculty of Pharmaceutical Sciences Fukuoka University, Japan

Cadmium Exposure Induces Prostaglandin E2 Release from Cultured Human Astrocytes through Cyclooxygenase 2 Up-regulation

[Speaker] Natnicha Jakramonpreeya:1
[Co-author] Suttinee Phuagkhaopong:2, Pornpun Vivithanaporn:2
1:Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Thailand, 2:Department of Pharmacology, Faculty of Science, Mahidol University, Thailand

Differential effects of heavy metals on CCL2 release from human astrocytes

[Speaker] Norapat Rungreangplangkool:1
[Co-author] Suttinee Phuagkhaopong:2, Thitima Kasemsuk:3, Ruedeemars Yubolphan:2, Pornpun Vivithanaporn:2
1:Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 2:Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand, 3:Faculty of Pharmaceutical Science, Burapha University, Chonburi, Thailand

Canola oil toxicity in SHRSP and its sex difference

[Speaker] Naoki Ohara:1
[Co-author] Mai Nishikawa:1, Risako Ninomiya:1, Yukiko Naito:2, Kenjiro Tatematsu:3, Yoshiaki Saito:4, Daisuke Miyazawa:1, Yoko Hashimoto:5, Hiroyuki Ohnishi:2, Harumi Okuyama:1
1:Toxicology, Kinjo Gakuin University, College of Pharmacy, Japan, 2:Kitasato University, School of Allied Health Sciences, Japan, 3:Laboratory of Radiochemistry, Gifu Pharmaceutical University, Japan, 4:Department of Pathology, Hatano Research Institute FDSC, Japan, 5:Department of Biochemistry, School of Dentistry, Aichi-Gakuin University, Japan

Hepatoprotective Effect of Capsicum frutescens Supplemented Diet against Acetaminophen Induced Liver Damage in Laboratory Animals

[Speaker] Ajibade E. Adesiyun:1
[Co-author] Erhirhie E. Oghenesuvwe:2, Ekene E. Nwoke:3
1:Department of Clinical Pharmacy & Bio-pharmacy, University of Lagos, Nigeria, 2:Department of Pharmacology and Therapeutics, Delta State University, Abraka, Delta State, Nigeria, 3:Department of Pharmacology and Toxicology, Nnamdi Azikiwe University, Agulu Campus, Anambra State, Nigeria

EGG WHITE HYDROLYSATE INHIBITS THE VASCULAR DYSFUNCTION AND THE RAISE ON BLOOD PRESSURE AFTER LONG-TERM ALUMINUM EXPOSURE IN RATS

[Speaker] Marta Miguel:1
[Co-author] Caroline S Martinez:2, Alyne G Escobar:2, Janaina Piagette:2, Silvia Moreno-Fernandez:1, Dalton V Vassallo:3, Frank M Pecanha:2, Giulia A Wiggers:2
1:Bioactividad y Analisis de Alimentos, Instituto de Investigacion en Ciencias de la Alimentacion (CIAL, CSIC-UAM), Madrid, Spain, 2:Postgraduate Program in Biochemistry, Universidade Federal do Pampa, Uruguaiana/RS, Brazil, 3:Department of Physiological Sciences, Universidade Federal do Espirito Santo, Vitoria/ES, Brazil

Sub-chronic toxicity studies on Methanol tuber extract of Chlorophytum alismifolium Baker (Liliaceae) in rats

[Speaker] Abdulhakim Abubakar:1
[Co-author] Abdullahi B. Nazifi:2, Fatima H. Ismail:1, Kehinde A. Duke:1, Theophillus U. Danjuma:1
1:Department of Pharmacology and Therapeutics, Ahmadu Bello University, Nigeria, 2:Department of Pharmacology and Therapeutics, Bayero University, Kano, Nigeria

Prevalence of Some Trace and Toxic Heavy Metals in Raw Cow's and buffaloe's Milk

[Speaker] Birendra K. Roy:1
1:Dept. of Pharmacology and Toxicology, Faculty of Veterinary Science & A. H., B. A. U., Ranchi-834006, India

Toxicological Evaluation of Undetoxified and Detoxified Seed Oil of Jatropha curcas Linn (Euphorbiaceae)

[Speaker] Helen O. Kwanashie:1
[Co-author] Shola P. Emiade:1, Benjamin A. Chindo:2, Janet I. Ejiofor:1
1:Dept. of Pharmacology & Therapeutics, Ahmadu Bello University, Nigeria, 2:Dept. of Pharmacology & Toxicology, Kaduna State University, Nigeria

Anthracycline antibiotics, doxorubicin impacts on the fusion of autophagosome with lysosme on the autophagic flux

[Speaker] Noriko Toda:1
[Co-author] Takeya Sato:2, Guanjie Li:2, Masanori Yamauchi:1, Teruyuki Yanagisawa:2
1:Anesthesiology and Perioperative medicine, Tohoku University Graduate School of Medicine, Japan, 2:Molecular pharmacology, Tohoku University Graduate School of Medicine, Japan

Mechanisms underlying neurodevelopmental and immunological toxicity in the mouse neocortex following prenatal exposure to ethanol

[Speaker] Munekazu Komada:1
[Co-author] Shoshiro Okada:1
1:Department of Parmacology, Aichi Medical University, Japan

Sigma-1, MT1 and MT3 receptor agonist attenuates pre- and postnatal abnormalities induced by cyclophosphamide, tobacco smoking, ethanol, peat smoke pollution and gestational diabetes in rats offspring

[Speaker] Anna S. Solomina:1
[Co-author] Shreder Ol'ga V.:1, Ekaterina D. Shreder:1, Viktoria V. Zabrodina:1, Dinara M. Gorbatova:1, Andrey D. Durnev:1
1:Drug Toxicology, FSBI “Research Zakusov Institute of Pharmacology”, Russia

Testicular toxicity of a commercial polyherbal product in male albino rats

[Speaker] Emmanuel U. Etuk:1
[Co-author] Maxwell O. Egua:2
1:Pharmacology & Therapeutics, Usmanu Danfodiyo University, Sokoto, Nigeria, 2:Pharmacology & Therapeutics, University of Abuja, Abuja, Nigeria

ANTIOXIDANT AND HEPATOPROTECTIVE POTENTIALS OF ETHYLACETATE AND METHANOL FRACTIONS OF Lannea barteri Oliv. (Anarcadiaceae) LEAF EXTRACT

[Speaker] Bonaventure C Obi:1
[Co-author] Florence N Mbaoji:1, Adaobi C Ezike:1, Chukwuemeka S Nworu:1, Collins A Onyeto:1, Okechukwu O Ndu:1, Ifeoma A Nwabunike:1, Akachukwu M Onwuka:1, David S Ani:1, Gabriel C Nwatu:1
1:Department of Pharmacology and Toxicology, Faculty of Pharmaceutical Sciences, University of Nigeria Nsukka, Enugu State, Nigeria

Toxic Mn and Pb in Drinking Water From Illegal Gold Mining Area in Sumatera, Indonesia

[Speaker] Cimi Ilmiawati:1
[Co-author] Husna Yetti:2, Mohamad Reza:3
1:Dept. of Pharmacology, Faculty of Medicine, Andalas University, Indonesia, 2:Dept. of Public Health, Faculty of Medicine, Andalas University, Indonesia, 3:Dept. of Biology, Faculty of Medicine, Andalas University, Indonesia

Cohort study of liver toxicity of azole antifungal medication in a real-life hospital setting

[Speaker] Tonny S Petersen:1
[Co-author] Kim P Dalhoff:1
1:Clinical Pharmacology, Bispebjerg and Frederiksberg University Hospital, Copenhagen, Denmark

Cytotoxic effects of menthol in lung cancer cell line, A549

[Speaker] Kenji Takahashi:1
[Co-author] Toshio Ohta:1
1:Department of Veterinary Pharmacology, Faculty of Agriculture, Tottori University, Japan

Dietary Factors Modulate Gastrointestinal Adverse Effects of Methotrexate

[Speaker] Takashi Higuchi:1
[Co-author] Mika Yoshimura:1, Shomi Oka:1,2, Aya Kawasaki:1, Eiji Warabi:3, Seiya Mizuno:4, Masao Ono:5, Satoru Takahashi:6, Shigeto Tohma:2, Naoyuki Tsuchiya:1, Hiroshi Furukawa:1,2
1:Molecular and Genetic Epidemiology Laboratory, Faculty of Medicine, University of Tsukuba, Japan, 2:Clinical Research Center for Allergy and Rheumatology, National Hospital Organization Sagamihara National Hospital, Japan, 3:Environmental Molecular Biology Laboratory, Faculty of Medicine, University of Tsukuba, Japan, 4:Laborarory Animal Resource Center, University of Tsukuba, Japan, 5:Department of Clinical Laboratory, National Hospital Organization Mito Medical Center, Japan, 6:Department of Anatomy and Embryology, Faculty of Medicine, University of Tsukuba, Japan

Modulation of unfolded protein response by methylmercury (MeHg)

[Speaker] Hideki Hiraoka:1
[Co-author] Kengo Nakahara:1, Kosaku Okuda:1, Yoshito Kumagai:2, Takashi Uehara:1
1:Department of Medicinal Pharmacology, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Japan, 2:Doctoral Program in Biomedical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan

Effects of neonicotinoid and organophosphorus insecticides on macrophage functions

[Speaker] Kanako Sasou:1
[Co-author] Miyoko Matsushima:1, Nanako Ogasawara:1, Tomoko Ohdachi:3, Kazuko Atsumi:1, Kyohka Tanaka:1, Tomoshi Sugiyama:2, Jun Ueyama:1, Naozumi Hashimoto:3, Tsutomu Kawabe:1
1:Department of Pathophysiological Laboratory Sciences, Nagoya University Graduate School of Medicine, Japan, 2:Department of Thoracic Surgery, Nagoya University Graduate School of Medicine, Japan, 3:Department of Respiratory Medicine, Nagoya University Graduate School of Medicine, Japan

Nickel chloride suppresses cell proliferation and induces G2/M cell-cycle arrest in cultured human astrocytes

[Speaker] Ruedeemars Yubolphan:1
[Co-author] Pornpun Vivithanaporn:1
1:Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Acetaminophen-induced liver injury in normal and obese rats: comparison of oxidative stress and inflammation in the mechanism of toxicity

[Speaker] Chin-Lin Hsu:1
[Co-author] Wei-Tang Chang:2, Chun-Han Chang:1, Yi-Chen Chen:3, Yuan-Yen Chang:4, Hui-Wen Lin:5
1:Department of Nutrition, Chung Shan Medical University, Taiwan, 2:Department of Nutrition and Health Sciences, Chinese Culture University, Taiwan, 3:Department of Animal Science and Technology, National Taiwan University, Taiwan, 4:Department of Microbiology and Immunology, School of Medicine, Chung Shan Medical University, Taiwan, 5:Department of Optometry, Asia University, Taiwan

Role of Acetaldehyde in Ethanol Reversal of Morphine Tolerance

[Speaker] Rob Hill:1
[Co-author] Alexandre Conibear:1, Eamonn Kelly:1, William L Dewey:2, Graeme Henderson:1
1:University of Bristol, UK, 2:Virginia Commonwealth University, USA

Protective effects of Glyphaea brevis leaves on cell viability and markers of Sertoli cells in DNB-induced toxicity

[Speaker] Janet O Sangodele:1
[Co-author] Mary Olaleye:1, Afolabi Akinmoladun:1
1:Biochemistry, Federal University of Technology, Akure, Nigeria

Argan Oil and Syzygium aromaticum Essential oil Improves Biochemical and Liver, kidney and brain Histological Changes Induced by Hydrogen Peroxide

[Speaker] Badiaa Lyoussi:1
[Co-author] Meryem Bakour:1, Najoua Soulo:1, Nawal Hammas:2,3, Hind Elfatemi:2,3, Abderrazak Aboulghazi:1, Amal Tarop:1, Abdelfattah Abdellaoui:1, Noori Alwaili:4
1:Laboratory of Physiology Pharmacology and Environmental Health, Department of Biology, Faculty of Sciences Dhar Mehraz, University Sidi Mohamed Ben Abdellah, Fez, Morocco, 2:Laboratory of Biomedical and Translational Research, Faculty of Medicine and Pharmacy, University Sidi Mohamed Ben Abdellah, Fez, Morocco, 3:Department of pathology, University Hospital Hassan II, Fez, Morocco, 4:New York Medical Care for Nephrology, New York, USA

In vivo acute and subchronic toxicity studies of methanolic extract obtained from roots of Diospyros melanoxylon L

[Speaker] Vaishali Manikrao Patil:1
[Co-author] Neeraj Masand:2
1:KIET School of Pharmacy, KIET Group of Institutions, India, 2:Department of Pharmacy, Lala Lajpat Rai Memorial Meedical College, Meerut, UP, India

Statin-induced cytotoxicity through a mevalonate-independent mechanism

[Speaker] Jae Won Choi:1
[Co-author] Hyoshik Shin:1, Jichang Seong:1, Junghan Yoon:2
1:Pharmacology, Yonsei University Wonju College of Medicine, Korea, 2:Internal Medicine, Yonsei University Wonju College of Medicine, Korea

Cooperative effects of UVA irradiation on TiO2 nanoparticles-induced cell death in mammalian skin epidermal cells

[Speaker] Yoshihiro Higuchi:1
[Co-author] Ayako Furukawa:1, Natsuki Kamimura:1, Rikako Ikeda:1, Yumi Nakashima:1
1:Faculty of Pharmaceutical Sciences, Suzuka University of Medical Sciences, Japan

Low-dose tributyltin exposure induces an oxidative stress-triggered JNK-related pancreatic beta-cell apoptosis and a reversible hypoinsulinemic hyperglycemia in mice

[Speaker] Shing-Hwa Liu:1
[Co-author] Chun-Fa Huang:2, Jing-Ren Tsai:1, Meng-Tsan Chiang:3, Kuo-Cheng Lan:4
1:National Taiwan University, Taiwan, 2:China Medical University, Taiwan, 3:National Taiwan Ocean University, Taiwan, 4:Tri-Service General Hospital, Taiwan

Tributyltin induces dose- and phase of growth-related alterations in eukaryotic cell proliferation and carbohydrate levels

[Speaker] Maria Kakolyri:1
[Co-author] Aikaterini Margaritou:1, Ekaterini Tiligada:1
1:Department of Pharmacology, Medical School, National and Kapodistrian University of Athens, Greece

ACUTE TOXICITY OF Urena lobata LEAF EXTRACT ON EMBRYO, JUVENILE AND ADULT OF ZEBRA FISH (Danio rerio)

[Speaker] Yudi Purnomo Roespandi:1
[Co-author] Noer Aini:2, Moch. Aris Widodo:1,3
1:Medical Pharmacology and Pharmacy, Faculty of Medicine Islamic University of Malang, Indonesia, 2:Medical Parasitology, Faculty of Medicine Islamic University of Malang, Indonesia, 3:Medical Pharmacology, School of Medicine Brawijaya University, Indonesia

ACUTE TOXICITY OF NEW COMPOUND -TARTRATOGERMANATE ZINC

[Speaker] Petro Antonenko:1
[Co-author] Galyna Paniotova:1, Vladlena Godovan:1, Inna Seifullina:2, Olena Chebanenko:2
1:General and Clinical Pharmacology, Odessa National Medical University, Ukraine, 2:Department of General Chemistry and Polymers, Odessa I. I. Mechnikov National University, Ukraine

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