Sessions

Sodium acetate improves disrupted glucoregulation and hepatic lipid accumulation in insulin-resistant female rats: involvement of adenosine deaminase and dipeptidyl peptidase-4 activities

[Speaker] Lawrence A. Olatunji:1
[Co-author] Tolulope E Omolekulo:1, Olugbenga S Michael:1
1:HOPE Cardiometabolic Research Team, Department of Physiology, University of Ilorin, Nigeria

Effect of culture gas pressure on 3T3-L1 preadipocytes differentiation

[Speaker] Yuki Tsuchihashi:1
[Co-author] Licht Miyamoto:1, Masayuki Shono:2, Koichiro Tsuchiya:1
1:Department of Medical Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate school, Japan, 2:Support Center for Advanced Medical Sciences, Institute of Biomedical Sciences, Tokushima University Graduate school, Japan

Visualization of advanced glycation end-products phagocytosis by macrophages and identification of possible receptor

[Speaker] Shinichi Hamasaki:1
[Co-author] Takuro Kobori:2, Atsuhiro Kitaura:1, Yui Yamazaki:2, Takashi Nishinaka:2, Atsuko Niwa:2, Shinichi Nakao:1, Masahiro Nishibori:3, Hideo Takahashi:2
1:Department of Anesthesiology, Kindai University, Faculty of Medicine, Japan, 2:Department of Pharmacology, Kindai University, Faculty of Medicine, Japan, 3:Department of Pharmacology, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan

Inhibition of adenosine deaminase and xanthine oxidase activities by sodium acetate ameliorates glucose dysregulation and defective antioxidant defenses induced by gestational excess androgen in rats

[Speaker] Lawrence A Olatunji:1
[Co-author] Emmanuel D Areola:1, Olufunto O Badmus:1, Taofeek O Usman:1, Inkyeom Kim:2
1:University of Ilorin, Nigeria, 2:Kyungpook National University School of Medicine, Korea

Treatment of rats with the antipsychotics sulpiride develops dopamine D2 receptor-independent fatty liver: role of adipose tissue insulin resistance

[Speaker] Chunxia Wang:1
[Co-author] Yuhao Li:2
1:Pharmacy, Nanfang Hospital, Southern Medical University, China, 2:Endocrinology and Metabolism Group, Sydney Institute of Health Sciences/Sydney Institute of Traditional Chinese Medicine, NSW 2000, Australia

Prevention of antipsychotic-induced hyperglycemia by vitamin D: a data mining prediction followed by experimental exploration of the molecular mechanism

[Speaker] Takuya Nagashima:1
[Co-author] Takayuki Nakagawa:2, Shuji Kaneko:1
1:Graduate School of Pharmaceutical Sciences, Kyoto University, Japan, 2:Department of Clinical Pharmacology and Therapeutics, Kyoto University Hospital, Japan

A novel Nrf2 activator RS9 protects ARPE-19 cells from oxidative stress induced by NaIO3 via autophagic pathway

[Speaker] Yuichi Saito:1
[Co-author] Shinsuke Nakamura:1, Masamitsu Shimazawa:1, Hideaki Hara:1
1:Biofunctional Evaluation, Gifu Pharmaceutical University, Japan

Barley b-glucan improves metabolic condition via short-chain fatty acids produced by gut microbial fermentation

[Speaker] Keita Watanabe:1
[Co-author] Satsuki Taira:1, Junki Miyamoto:1, Ikuo Kimura:1
1:Tokyo University of Agriculture and Technology Graduate School of Agriculture, Japan

Circadian disruption during the late gestation period does not affect offspring birth weight

[Speaker] Takashi Yasuoka:1
[Co-author] Licht Miyamoto:1, Yuki Tsuchihashi:1, Tsubasa Sone:1, Shiori Masuda:1, Koichiro Tsuchiya:1
1:Department of Medical Pharmacology, Institute of Biomedical Sciences, Tokushima University Graduate School, Japan

Circadian rhythms and metabolic disorders: an epigenetic approach

[Speaker] Dragos I Mosneagu:1
[Co-author] Hashmeena Sanghani:1, Sridhar Vasudevan:1
1:Department of Pharmacology, University of Oxford, UK

Prostaglandin E receptor subtype 4 regulates bile acid synthesis and its activation protects against hypercholesterolemia

[Speaker] Fan Ying:1,2
[Co-author] Yin Cai:2, Hoi Kin Wong:1, Xin Yi Chen:1, Paul M Vanhoutte:1, Aimin Xu:1,3, Eva Hoi Ching Tang:1,4
1:Department of Pharmacology and Pharmacy and State Key Laboratory of Pharmaceutical Biotechnology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 2:Department of Anesthesiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 3:Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, 4:School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong

Berberine stimulates FGF21 expression via activation of AMP-activated protein kinase in brown and beige adipocytes

[Speaker] Yuhei Mitani:1
[Co-author] Takao Hirai:1, Michiyo Takagi:1, Ken-Ichi Nakashima:1, Makoto Inoue:1
1:Laboratory of Medicinal Resources, School of Pharmacy, Aichi Gakuin University, Japan

Combination of amino acids necessary and sufficient for the optimal activation of mTORC1

[Speaker] Ryuichi Ohgaki:1
[Co-author] Chunhuan Jin:1, Suguru Okuda:1, Shushi Nagamori:1, Yoshikatsu Kanai:1
1:Department of Bio-system Pharmacology, Graduate School of Medicine, Osaka University, Japan

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR (GLP-1R) AGONIST CONTRIBUTES TO BONE TURNOVER REBALANCING IN HYPERCALORIC DIET-INDUCED OBESITY

[Speaker] Paulo F Silveira:1
[Co-author] Patricia L Alves:1, Rafaela F Alponti:1
1:Laboratory of Pharmacology, Comparative and Translational Physiology Unit, Instituto Butantan, Brazil

GLUCAGON-LIKE PEPTIDE 1 RECEPTOR (GLP-1R) ANTAGONIST IMPAIRS BONE TURNOVER IN HYPERCALORIC DIET-INDUCED OBESITY

[Speaker] Paulo F Silveira:1
[Co-author] Patricia L Alves:1, Rafaela F Alponti:1
1:Laboratory of Pharmacology, Comparative and Translational Physiology Unit, Instituto Butantan, Brazil

JAK Signaling Inhibitor Induces Browning of White Adipose Tissue, and Improves Systemic Metabolic Health In Vivo

[Speaker] Kikid R. Qurania:1
[Co-author] Koji Ikeda:2, Keiko Yagi:2, Ken-Ichi Hirata:1, Noriaki Emoto:2
1:Department of Internal Medicine, Division of Cardiovascular Medicine, Kobe University, Japan, 2:Department of Clinical Pharmacy, Kobe Pharmaceutical University, Japan

The importance of peroxisome in obesity-related adipocyte injury

[Speaker] Songling Jiang:1
[Co-author] Lingjuan Piao:1, Hunjoo Ha:1
1:Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Korea

Programmed Necrosis of Adipocytes Induced by High-dose Osteocalcin

[Speaker] Masato Hirata:1
[Co-author] Takahito Otani:1, Akiko Mizokami:2, Norio Kitagawa:1, Eijiro Jimi:2, Tetsuichiro Inai:1
1:Fukuoka Dental College, Japan, 2:Kyushu University, Japan

Altered metabolism by a P450 oxidoreductase variant found in apparently normal population

[Speaker] Amit V Pandey:1,2
[Co-author] Shaheena Parween:1,2, Florence Roucher Boulez:3, Yves Morel:3
1:Pediatric Endocrinology, University Children's Hospital Bern, Switzerland, 2:Department of Biomedical Research, University of Bern, Bern, Switzerland, 3:Service d'Endocrinologie Moléculaire et Maladies Rares, Centre de Biologie et Pathologie Est, Hospices Civils de Lyon, Université Lyon 1, 69002 Bron-Lyon, France

Paeonol attenuates high glucose-induced expression of FN and ICAM-1 by promoting the activation of Nrf2/ARE pathway via upregulation of Sirt1 in GMCs

[Speaker] Zhiquan Chen:1
[Co-author] Lei Zhang:1, Wenyan Gong:1, Heqing Huang:1
1:School of Pharmaceutical Sciences, Sun Yat-sen University, China

25-hydroxyvitamin D and the risk of incident diabetes in Hong Kong Chinese

[Speaker] Raymond Yh Leung:1,2
[Co-author] Bernard My Cheung:1, Kathryn Cb Tan:1, Annie Wc Kung:1, Ching-Lung Cheung:2
1:Medicine, The University of Hong Kong, Hong Kong, 2:Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong

Correlations between vitamin D insufficiency and antipsychotic-induced metabolic anomalies in schizophrenic patients

[Speaker] Chien-Chih Chen:1
[Co-author] Li-Wen Hsu:1, Kuang-Tzu Huang:1, Yu-Chi Huang:1, Chin-Chuen Lin:1
1:Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taiwan

Study for chemical composition and wound repair activity of Bletilla formosana polysaccharide

[Speaker] Jing-Jy Cheng:1
[Co-author] Mei-Kuang Lu:1, Chi-Hsein Chao:1
1:National Research Institute of Chinese Medicine, Taiwan

Periodic variation in bile acids controls circadian changes in serum uric acid levels via regulation of hepatic expression of xanthine oxidase in mice

[Speaker] Satoru Koyanagi:1
[Co-author] Takumi Kanemitsu:1, Yuya Tsurudome:1, Naoki Kusunose:1, Masayuki Oda:1, Naoya Matsunaga:1, Shigehiro Ohdo:1
1:Pharmaceutics/Glocal Healthcare Science, Kyushu University, Japan

The antihyperlipidemic and antihyperglycemic effects of ginseng flower in high fructose-fed rat via upregulation of hepatic PPAR-gamma expression

[Speaker] Chi-Rei Wu:1
[Co-author] Zi-Wei Chao:1, Nai-Wen Mei:2, Hsueh-Hung Shao:1
1:Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taiwan, 2:Gincare INT'L ENT. Co., LTD., Taiwan

Effect of the silencing of TNF alpha and glycine receptors on the secretion of pro-inflammatory cytokines in 3T3-L1 preadipocytes

[Speaker] Rodrigo Romero-Nava:1
[Co-author] Erika Contreras-Nunez:1, Gerardo Blancas-Flores:1, Julio C. Almanza-Perez:1, Abraham Giacoman-Martinez:1, Ruben Roman-Ramos:1, Fengyang Huang:2, Francisco J. Alarcon-Aguilar:1
1:Ciencias Biologicas y de la Salud, Universidad Autonoma Metropolitana Unidad Iztapalapa, Mexico, 2:Departamento de Farmacologia y Toxicologia, Hospital Infantil de Mexico Federico Gomez (HIMFG), CDMX, Mexico

Importance of Heparan Sulfate in Adipose Tissue

[Speaker] Takuro Matsuzawa:1
[Co-author] Takeo Yoshikawa:1, Kazuhiko Yanai:1
1:Pharmacology, Tohoku University Graduate School of Medicine, Japan

Histone deacetylase inhibition attenuates hepatic steatosis in rats with experimental Cushing syndrome

[Speaker] InKyeom Kim:1
[Co-author] Mina Kim:1
1:Pharmacology, Kyungpook National University School of Medicine, Korea

Hypolipidemic Effect of XH601 on Hamsters of Hyperlipidemia and its Potential Mechanism

[Speaker] Mengjie Zhao:1
[Co-author] Hong Xiao:1
1:Department of Neuro-Psychiatric Institute, The Affiliated Brain Hospital of Nanjing Medical University, China

Can anticholinergics influence insulinotropic actions of incretins?

[Speaker] Sandeep Lahiry:1
[Co-author] Mitali Chatterjee:1, Sudip Chatterjee:2
1:Pharmacology, Institute of Post Graduate Medical Education & Research, Kolkata, India, 2:Vivekananda Institute of Medical Sciences, Kolkata, India

Crucial role of STARD10 in regulating lipid storage in mouse model of nonalcoholic steatohepatitis (NASH)

[Speaker] Masanori Ito:1
[Co-author] Taichiro Tomida:1, Yoshinori Mikami:1, Shingo Murakami:1, Satomi Adachi-Akahane:1
1:Department of Physiology, Faculty of Medicine, Toho University, Japan

PAQR3 regulates high glucose-induced expressions of fibronectin, ICAM-1 via NF-kappa B signaling pathway

[Speaker] Heqing Huang:1
[Co-author] Yezi Zou:1, Wenyan Gong:1, Zhiquan Chen:1
1:School of Pharmaceutical Sciences, Sun Yat-sen University, China

Pentamethylquercetin counteracts obesity and drives brown fat-like phenotype through AMPK-mediated activation of PGC-1 alpha/FNDC5 pathway in muscle

[Speaker] Hui Liu:1
[Co-author] Jian-Zhao Wu:1, Jing-Xia Du:1, Man-Wen Jin:1
1:School of Basic Medicine, Tongji Medical College, Huazhong University of Science and technology, China

Pigment epithelium-derived factor negatively regulates CD36 expression and lipid accumulation in non-alcoholic fatty liver disease

[Speaker] Kuang-Tzu Huang:1,2
[Co-author] Li-Wen Hsu:2, Chien-Chih Chen:3, Kuang-Den Chen:1,2, Chih-Che Lin:2, Chao-Long Chen:2
1:Institute for Translational Research in Biomedicine, Kaohsiung Chang Gung Memorial Hospital, Taiwan, 2:Liver Transplantation Center, Department of Surgery, Kaohsiung Chang Gung Memorial Hospital, Taiwan, 3:Department of Psychiatry, Kaohsiung Chang Gung Memorial Hospital, Taiwan

Involvement of 5α-reductase-mediated progesterone metabolism in the decidualization of human endometrial stromal cells

[Speaker] Mikihiro Yoshie:1
[Co-author] Kazuhiro Tamura:1, Tsubasa Chiba:1, Sayaha Nakajima:1, Naoko Kuwabara:1, Eiichi Tachikawa:2, Keiichi Isaka:2, Hirotaka Nishi:2
1:Department of Endocrine and Neural Pharmacology, Tokyo University of Pharmacy and Life Sciences, Japan, 2:Department of Obstetrics and Gynecology, Tokyo Medical University, Japan

Effect of TR3370, a quipazine analog, over glycemia in healthy and streptozotocin hyperglicemic rats

[Speaker] Itzel S. De La Rosa:1
[Co-author] Enrique Hong:1
1:Farmacobiologia, Centro de Investigacion y de Estudios Avanzados del I. P. N., Mexico

TRPV2 channel expressed in brown adipocyte is involved in thermogenesis

[Speaker] Kunitoshi Uchida:1,2
[Co-author] Wuping Sun:2, Jun Yamazaki:1, Makoto Tominaga:2
1:Department of Physiological Science and Molecular Biology, Fukuoka Dental College, Japan, 2:Division of Cell Signaling, National Institute for Physiological Sciences, Japan

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