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POPULATION PHARMACOKINETICS OF GENTAMICIN IN PUPPIES DIAGNOSED WITH PARVOVIRUS ENTERITIS

[Speaker] Fidelis A. Gberindyer:1
[Co-author] Abatan M. Oluwole:2, Shima K. Felix:3, Paolo Denti:4
1:Veterinary Physiology, Pharmacology and Biochemistry, Federal University of Agriculture, Makurdi, Nigeria, 2:Veterinary Pharmacology and Toxicology, University of Ibadan, Ibadan, Nigeria, 3:Gan-Rovet Animal Hospital, Warri, Nigeria, 4:Pharmacometrics Unit, Division of Clinical Pharmacology, Department of Medicine, University of Cape Town, South Africa

Implications of inter-correlation between hepatic CYP3A4-CYP2C8 enzymes for the evaluation of drug-drug interactions: a case study with repaglinide and gemfibrozil

[Speaker] Kosuke Doki:1,2
[Co-author] Adam S. Darwich:2, Brahim Achour:2, Aleksi Tornio:3, Janne T. Backman:3, Amin Rostami-Hodjegan:2,4
1:Department of Pharmaceutical Sciences, Faculty of Medicine, University of Tsukuba, Japan, 2:Centre for Applied Pharmacokinetic Research, University of Manchester, UK, 3:Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Finland, 4:Simcyp Limited (A Certara Company), UK

Population pharmacodynamic analysis of olmesartan medoxomil based on electronic medical records

[Speaker] Shota Muraki:1
[Co-author] Kunio Maema:1,2, Ayano Tomimatu:1, Yushi Kashihara:1, Takeshi Hirota:1, Ichiro Ieiri:1
1:Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan, 2:Yame General Hospital, Japan

Modeling the Auto-inhibition of Drug X Metabolism During Oral Administration

[Speaker] Atsuko Kawazoe:1
[Co-author] Tomoo Funaki:1, Seongryul Kim:1
1:Clinical Pharmacology Department of Clinical mamagement Headquarters of Clinical Development, Otsuka Pharmacrutical Co., Ltd., Japan

Predictive performance of physiologically-based pharmacokinetic model for amiodarone and its active metabolite: evaluation using therapeutic drug monitoring data from Japanese patients

[Speaker] Naoaki Hashimoto:1,2
[Co-author] Kosuke Doki:1,2, Kazutaka Aonuma:3, Masato Homma:1,2
1:Pharmacy, University of Tsukuba hospital, Japan, 2:Department of Pharmaceutical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan, 3:Department of Cardiology, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Japan

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