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CPAP promotes angiogenesis via interacting with and enhancing the activity of STAT3 in HCC

[Speaker] Liang-Yi Hung:1
[Co-author] Ruo-Yu Chen:1, Chia-Jui Yen:1, Yao-Wen Liu:2, Yih-Jyh Lin:1
1:National Cheng Kung University, Taiwan, 2:Kuo General Hospital, Taiwan

Inhibition of autophagy enhances Dihydroartemisinin (DHA)-induced cytotoxicity

[Speaker] Mei-Chuan Chen:1,2
[Co-author] Ruo-Wei Lee:2, Tung-Yun Wu:1
1:Ph. D. Program for the Clinical Drug Discovery from Botanical Herbs, College of Pharmacy, Taipei Medical University, Taiwan, 2:Graduate Institute of Pharmacognosy, College of Pharmacy, Taipei Medical University, Taiwan

Pharmacological activities of cyclooxygenase (COX) inhibitors against chlolangiocarcinoma

[Speaker] Wanna Chaijaroenkul:1,2
[Co-author] Kesara Na-Bangchang:1,2
1:Chulabhorn International College of Medicine, Thammasat University, Thailand, 2:Center of Excellence in Pharmacology and Molecular Biology of Malaria and Cholangiocarcinoma, Thailand

CXCR7/CXCR4 heterodimer-induced histone demethylation: a new mechanism of colorectal tumorigenesis

[Speaker] Xianjun Qu:1
[Co-author] Zhiyu Song:1, Feng Wang:2, Shuxiang Cui:2
1:Department of Pharmacology, School of Basic Medical Sciences, Capital Medical University, Beijing, China, 2:Toxicology and Sanitary Chemistry, School of Public Health, Capital Medical University, Beijing, China

Withdrawn

(Pro) renin receptor promotes colorectal cancer through the Wnt/β-catenin signaling pathway despite constitutive pathway component mutations

[Speaker] Akira Nishiyama:1
[Co-author] Yuki Shibayama:1, Zhiyu Wang:2, Juan Wang:1,2
1:Department of Pharmacology, Kagawa University Medical School, Japan, 2:Department of Immuno-oncology, Fourth Hospital of Hebei Medical University, Shijiazhuang, P. R. China

Supramolecular Nanofibers of Curcumin for Highly Amplified Radiosensitization of Colorectal Cancers to Ionizing Radiation

[Speaker] Huae Xu:1
[Co-author] Xiaolin Li:2, Dan Ding:3
1:Department of Pharmacy, the First Affiliated Hospital with Nanjing Medical University, China, 2:Department of Geriatric Gastroenterology, the First Affiliated Hospital with Nanjing Medical University, China, 3:State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education and College of Life Sciences, Nankai University, Tianjin, China

Unconventional EGF signal, EGF-KITENIN/ErbB4-AP-1 axis can confer resistance to cetuximab in colorectal cancer

[Speaker] Kyung Keun Kim:1
[Co-author] Jeong A Bae:1, Yoo-Seung Ko:1, Ik Joo Chung:2, Hangun Kim:3
1:Pharmacology, Chonnam National University Medical School, Korea, 2:Hematology-Oncology, Chonnam National University Medical School, Korea, 3:College of Pharmacy, Sunchon National University, Korea

DELAYED TOXICITY OF NIGERIAN CRUDE OIL

[Speaker] Udeme O Georgewill:1
[Co-author] Corelius Alozie:1, Owunari A Georgewill:1
1:PHARMACOLOGY, University Of Port Harcourt, Nigeria

Differential effects of purinergic signalling in Gastric Cancer derived cells through P2Y and P2X receptors

[Speaker] Claudio Coddou:1
[Co-author] M. Jose Hevia:1, Patricio Castro:1, Felipe Rodriguez:2, Claudia Robles:2, Erwin De La Fuente:1, Sebastian Ramirez:1, Giuliano Bernal:1
1:Biomedical Sciences, Universidad Catolica del Norte, Chile, 2:Biology, Universidad de Santiago de Chile, Chile

The chemotherapeutic potential of isoliquiritigenin in treating pancreatic cancer involving multiple mechanistic targets

[Speaker] Joshua K Ko:1
1:School of Chinese Medicine, Hong Kong Baptist University, Hong Kong

Different antitumor effects of JPH 203 in gastrointestinal cancer cells

[Speaker] Yasuhide Muto:1,2
[Co-author] Tomomi Furihata:1, Kentarou Okunishi:1, Yoshie Reien:1, Hanae Morio:1, Kousuke Higuchi:1, Sinichi Sakamoto:1, Hisahiro Matsubara:2, Naohiko Anzai:1
1:Department of Pharmacology, Chiba University Graduate School of Medicine, Japan, 2:Department of frontier surgery, Chiba University Graduate School of Medicine, Japan

Novel nanofibers for co-delivery of Paclitaxel and Tetrandrine with synergistic anticancer efficiency for gastric cancer

[Speaker] Xiaolin Li:1
[Co-author] Na Yu:1, Weihao Sun:1
1:Department of Geriatric Gastroenterology, the First Affiliated Hospital with Nanjing Medical University, China

RAGE inhibitors and gemcitabine: an effective combination to attenuate pancreatic cancer

[Speaker] Priyanka Swami:1
[Co-author] Estelle Leclerc:1, Michael Hollingsworth:2, James Grunkemeyer:2, Prakash Radhakrishnan:2, Tom Caffrey:2, Prathamesh Patil:2, Simon Shin:2, Ayrianne Crawford:2, Kelly Connell:2
1:Pharmaceutical Sciences, North Dakota State University, USA, 2:University of Nebraska Medical Center, USA

Effects of the C1 domain-targeted PKC modulator HMI-1a3 on the viability of colon cancer cells in culture

[Speaker] Ilari M E Tarvainen:1
[Co-author] Rebecca Nunn:1, Maria H Jaentti:1, Virpi Talman:1, Raimo K Tuominen:1
1:Drug Research Program, Division of Pharmacology and Pharmacotherapy, Faculty of Pharmacy, University of Helsinki, Finland

Assessment of quality of life in advanced gastro-intenstinal cancer patients receiving chemotherapy

[Speaker] Ritu Bala:1
[Co-author] Harminder Singh:1, Kuhu Verma:1
1:Pharmacology, no, India

Anti-tumor mechanisms of WMJ-J2, a novel aliphatic hydroxamate-based compound, in HCT116 colorectal cancer cells

[Speaker] Ming-Jen Hsu:1
[Co-author] Wei-Jan Huang:2, Yu-Han Huang:3, Meng-Chieh Yu:1
1:Department of Pharmacology, Taipei Medical University, Taiwan, 2:Graduate Institute of Pharmacognosy, Taipei Medical University, Taiwan, 3:Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan

RhoC/ROCK2 promotes vasculogenic mimicry formation through ERK/MMP and FAK/paxillin signaling pathways in hepatocellular carcinoma

[Speaker] Ji-Gang Zhang:1
[Co-author] Xue Zhang:1, Qin Li:1, Gao-Lin Liu:1
1:Department of Clinical Pharmacy, Shanghai General Hospital, Shanghai Jiao Tong University School of medicine, China

Epigenetic silencing of miR-483-3p promotes acquired gefitinib resistance in EGFR-mutant NSCLC by targeting integrin beta3

[Speaker] Lu Xu:1
[Co-author] Jinnan Yue:1, Dacheng Lv:1, Caiyun Wang:1, Hongzhuan Chen:1
1:Shanghai Jiao Tong University School of Medicine, China

Induction of apoptosis, cell proliferation, and cell cycle arrest by leukotriene receptor antagonists in triple negative breast cancer cells

[Speaker] Ruedeemars Yubolphan:1
[Co-author] Kran Suknuntha:1, Kanokpan Krueaprasertkul:1, Pornpun Vivithanaporn:1
1:Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok, Thailand

Transition metal complexes/organometallic compounds as anticancer/anti HIV drugs or in pharmaceutical industry

[Speaker] Prakash M Kinthada:1
1:Chemistry, sri vidyanikethan engineering college, India

CXCR4/SDF-1 EXPRESSION IN HER2/NEU BREAST CANCER BIOPSIES AND ITS RELATION TO ADJUVANT TREATMENT

[Speaker] Maria C Zimmermann:1,2
[Co-author] Natalia C Ayala:1,2,3,4, Melina Lorenzini Campos:2, Maria A Martinez:2, Angel E Alsina:2, Mariana Mr Gomez Pescie:2
1:Pharmacology, School of Medicine. Universidad Nacional del Nordeste, Argentina, 2:Medical Genomics, School of Medicine. Universidad Nacional del Nordeste, Argentina, 3:Clinical Oncology, School of Medicine. Universidad Nacional del Nordeste, Argentina, 4:J. R. Vidal Hospital. School of Medicine. Universidad Nacional del Nordeste, Argentina

Effect and mechanism of EGCG on the inflammation related cancers

[Speaker] Xue-jun LI:1
[Co-author] Yilixiati Xiaokaiti:1
1:Dept. of Pharmacology, School of Basic Medical Sciences, Peking University, China

Stabilization of SDF-2 by Hsp72 contributes to oxaliplatin resistance in human gastric cancer cells

[Speaker] Masako Tanaka:1
[Co-author] Katsuyuki Takahashi:2, Katsuyuki Miura:3, Shuhei Tomita:4, Nobuhito Goda:1, Masayuki Shiota:5
1:Dept. Life Sci. Med. BioSci., Sch. Sci. Eng., Waseda Univ., Japan, 2:Dept. Pharmacy, Osaka City Univ. Hosp., Japan, 3:Appl. Pharmacol. Ther., Osaka City Univ. Grad. Sch. Med., Japan, 4:Dept. Pharmacol., Osaka City Univ. Grad. Sch. Med., Japan, 5:Res. Sprt. Platf., Osaka City Univ. Grad. Sch. Med., Japan

Overexpression of CD44 standard isoform upregulates HIF-1alpha signaling in hypoxic breast cancer cells

[Speaker] Dayoung Ryu:1
[Co-author] In-Geun Ryoo:1, Mi-Kyoung Kawk:1
1:College of Pharmacy, The Catholic University of Korea, Korea

Targeting dysregulated mitochondrial fission pathways in triple negative breast cancer therapy

[Speaker] Angelique Nyinawabera:1
[Co-author] Smiti Gupta:1, Karthikeyan Chandrabose:1, Amit K Tiwari:1
1:Pharmacology and Experimental Therapeutics, The University of Toledo, College of Pharmacy and Pharmaceutical Sciences, USA

Possible anti-proliferative effect of TASK-3 on HEK293 and PANC-1 cells

[Speaker] Yoshihiro Konno:1
[Co-author] Makoto Sato:1, Yutaro Obara:1, Kuniaki Ishii:1
1:Department of Pharmacology, Yamagata University school of Medicine, Japan

Prolyl Hydroxylase inhibitor repaired chemo-sensitivity through tumor blood vessel normalization in tumor mouse model

[Speaker] Shinji Matsunaga:1
[Co-author] Shunji Nishide:1,2, Masayuki Shiota:3, Takehiro Yamaguchi:1, Shojiro Kitajima:1, Katsuyuki Takahashi:1, Katsuyuki Miura:4, Shuhei Tomita:1
1:Department of Pharmacology, Osaka City University Graduate School of Medicine, Japan, 2:Department of Urology, Osaka City University Graduate School of Medicine, Japan, 3:Division of Research support platform, Osaka City University Graduate School of Medicine, Japan, 4:Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Japan

Targeting ATM Enhances Triple Negative Breast Cancer Response to Chemotherapy

[Speaker] Rong Xu:1
[Co-author] Hancheng Mei:1, Lin Zhu:1, Jiaxiong Ming:1, Zhaocong Wang:1, Hui Chen:1, Haifa Shen:2,3
1:Department of Pharmacology, Tongji Medical College, Huazhong University of Science and Technology, China, 2:Department of Nanomedicine, Houston Methodist Research Institute, USA, 3:Department of Cell and Developmental Biology, Weill Cornell Medicine, USA

Phospholipase C-related catalytically inactive protein regulates phosphatidyl-inositol metabolism and modulates cancer cell migration

[Speaker] Takashi Kanematsu:1
[Co-author] Satoshi Asano:1, Yosuke Yamawaki:1, Satoru Kusaka:1
1:Department of Cellular and Molecular Pharmacology, Institute of Biomedical and Health Sciences, Hiroshima University, Japan

Comparative analysis of a two-dimensional and three dimensional model of BT-20 triple-negative breast carcinoma cells in response to an antiproliferative agent

[Speaker] Jie Wang:1
[Co-author] Duncan Allan Duncan:1, Iman Van Den Bout:2, Werner Cordier:1
1:Pharmacology, University of Pretoria, South Africa, 2:Physiology, University of Pretoria, South Africa

The tumor suppressor Merlin regulates fatty acid synthesis thus providing a field for targeted pharmacotherapy of neurofibromatosis type II

[Speaker] Dina S Stepanova:1
[Co-author] Nikolay Shimanovskiy:1, Jonathan Chernoff:2
1:Russian National Research Medical University, Russia, 2:Fox Chase Cancer Center, USA

MMP-9-responsive nanodiamond-based biosensor for enhanced metastatic tumor site detection

[Speaker] Mengjie Gu:1
[Co-author] Xin Wang:1, Tan Boon Toh:2, Nurrul Lissa Binti Abdullah:2, Edward Kai-Hua Chow:1,2
1:Pharmacology, National University of Singapore, Singapore, 2:Cancer Science Institute of Singapore, National University of Singapore, Singapore

Establishment of high metastatic evolved clone of adenocarcinoma cells with Mmp9 promoter-driven fluorescence reporter

[Speaker] Chiharu Sogawa:1
[Co-author] Takanori Eguchi:1,4, Yuka Okusha:1, Keisuke Nakano:2, Yuri Namba:1,3, Kazumi Ohyama:5, Norio Sogawa:6, Ken-Ichi Kozaki:1, Kuniaki Okamoto:1
1:Dental Pharmacology, Okayama University Graduate School of Medicine Dentistry and Pharmaceutical Sciences, Japan, 2:Oral Pathology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan, 3:Oral Radiology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan, 4:Advanced Research Center for Oral and Craniofacial Sciences, Okayama University Dental School, Japan, 5:RI Research Center, Okayama University Dental School, Japan, 6:Dental Pharmacology, Matsumoto Dental University, Japan

Circadian control of P-glycoprotein in Hepa1-6 hepatocarcinoma tumor cells and Hepa1-6 tumor-bearing mice

[Speaker] Narin Ozturk:1
[Co-author] Sandrine Dulong:2, Xiao-Mei Li:2, Francis Levi:3, Alper Okyar:1
1:Department of Pharmacology, Faculty of Pharmacy, Istanbul University, Turkey, 2:INSERM UMRS 935 Modeles de cellules souches malignes et therapeutiques, Campus CNRS, Villejuif-Cedex, France, 3:Warwick Systems Biology Centre, Warwick Medical School, Cancer Chronotherapy Unit, Coventry CV47AL, UK

Fluorescent imaging of in vivo H2O2 levels reveals contribution of oxidative microenvironment to tumor malignancy

[Speaker] Yoshifumi Ueda:1
[Co-author] Shigeki Kiyonaka:1, Keisuke Inoue:1, Yasuo Mori:1
1:Department of Synthetic Chemistry and Biological Chemistry, Graduate school of Engineering, Kyoto University, Japan

Knockdown of TM9SF4 triggering ER stress exerts anti-growth effect on drug-resistant breast cancer cells

[Speaker] Yifei Zhu:1
[Co-author] Xiaoqiang Yao:1
1:Chinese University of Hong Kong, Hong Kong

The Role of HPV Oncogenes in the Regulation of microRNA pathway in Cervical Cancer

[Speaker] Yi Song:1
[Co-author] Tao Tang:1, Yan Deng:1, Yi Zhao:1
1:Obstetrics & Gynaecology, The Chinese University of Hong Kong, China

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