Sessions

Identification of Polyphenolics from Bulbine abyssinica A. Rich Leaves

[Speaker] Samuel W Odeyemi:1
[Co-author] Anthony J Afolayan:1
1:Medicinal Plants and Economic Development (MPED) Research Center, Botany, University of Fort Hare, South Africa

Effect of new classes of antidiabetic drugs on cardiovascular outcomes in randomised controlled trials: a network meta-analysis

[Speaker] Yue Fei:1
[Co-author] Man-Fung Tsoi:1, Cyrus R Kumana:1, Tommy Tsang Cheung:1, Bernard Man Yung Cheung:1
1:Department of Medicine, The University of Hong Kong, Hong Kong

Comparative equivalence of Metformin brands available in Sokoto, Northwestern Nigeria

[Speaker] Abdulhakeem Adio Awesu:1
[Co-author] Bello Oricha Shaibu:1, Chika Aminu:1, Acho Mohammed:2, Akinleye Olushola Moshood:3
1:Department of Pharmacology and Therapeutics, College of Health Sciences, Usmanu Danfodiyo University, Sokoto, Nigeria, 2:Department of Pharmaceutical Microbiology, Faculty of Pharmaceutical Sciences, Usmanu Danfodiyo University., Nigeria, 3:Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Lagos, Nigeria

Mucuna pruriens Leaf Extracts Mediate Antidiabetic Properties via Multiple Mechanisms

[Speaker] Prabal K Chatterjee:1
[Co-author] Oke-Oghene Akpoveso:1, George W Olivier:1
1:School of Pharmacy & Biomolecular Sciences, University of Brighton, UK

Study on the mechanism of Iridoid Glycosides in Radix Rehmanniae and Cornus Officinalis intervention in Diabetic Nephropathy

[Speaker] Huiqin Xu:1
[Co-author] Xin Lv:1, Yuping Chen:1, Gaohong Lv:1, Yingxue Fu:1, Wenqing Bian:1
1:College of Pharmacy, Nanjing University of Chinese Medicine, China

AW, a novel HDAC inhibitor, as a potential therapy for early-stage diabetic retinopathy

[Speaker] Po-Lin Liao:1,2
[Co-author] Ching-Hao Li:3,4,5, Chi-Hao Tsai:1, Ling-Shan Tse:2, Shih-Hsuan Huang:2, Yu-Wen Cheng:2, Jaw-Jou Kang:1,3
1:Institute of Food Safety and Health Risk Assessment, School of Pharmaceutical Sciences, National Yang-Ming University, Taiwan, 2:School of Pharmacy, Taipei Medicine University, Taipei, Taiwan, 3:Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan, 4:Department of Physiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan, 5:Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taipei, Taiwan

Selective placental growth factor (PlGF) inhibition: a novel pharmacological approach in diabetic retinopathy

[Speaker] Claudio Bucolo:1
[Co-author] Francesca Lazzara:1, Anna Fidilio:1, Salvatore Salomone:1, Filippo Drago:1
1:Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy

High concentrations of dipeptidyl peptidase-4 inhibitors suppressed lipopolysaccharide-induced inflammatory cytokine expression in U937 cells

[Speaker] Shiho Yamadera:1
[Co-author] Yuya Nakamura:2,4, Masahiro Inagaki:3, Isao Ohsawa:4, Yoshikazu Goto:4, Hiromichi Gotoh:4, Mayumi Tsuji:2, Shinichi Iwai:1, Yuji Kiuchi:2
1:Department of Healthcare and Regulatory Sciences, Showa University School of Pharmacy, Tokyo, Japan, 2:Department of Pharmacology, Showa University School of Medicine, Tokyo, Japan, 3:Department of Chemistry, College of Arts and Sciences, Showa University, Tokyo, Japan, 4:Saiyu Soka Hospital, Saitama, Japan

Molecular mechanism for negative regulation of insulin-stimulated Akt phosphorylation and glucose uptake by endothelin-1 in skeletal muscle cells

[Speaker] Takahiro Horinouchi:1
[Co-author] Yuichi Mazaki:1, Akimasa Hoshi:1, Koji Terada:2, Soichi Miwa:1
1:Department of Cellular Pharmacology, Graduate School of Medicine, Hokkaido University, Japan, 2:Department of Biochemistry and Molecular Biology, Shiga University of Medical Science, Japan

The methanolic extract of Thymus praecox subsp. skorpilii var. skorpilii restores glucose homeostasis and ameliorates insulin resistance on streptozotocin/nicotinamide-induced type 2 diabetic rats

[Speaker] Muhammet Emin Cam:1
[Co-author] Sila Yildiz:1, Ayse Nur Hazar-Yavuz:1, Busra Ertas:1, Turgut Taskin:2, Levent Kabasakal:1
1:Pharmacology, Faculty of Pharmacy, Marmara University, Turkey, 2:Pharmacognosy, Faculty of Pharmacy, Marmara University, Turkey

Effects of sacha inchi oil intake on lifestyle-related diseases in mice

[Speaker] Yukiko Naito:1
[Co-author] Hiroyuki Ohnishi:1, Naoki Ohara:2
1:School of Allied Health Sciences, Kitasato University, Japan, 2:College of Pharmacy, Kinjo Gakuin University, Japan

Comparative Efficacy and Safety of Gabapentin, Pregabalin, Oxcarbazepine and Duloxetine in Diabetic Peripheral Neuropathy - A Network Meta-Analysis

[Speaker] Karan B Shah:1
[Co-author] Devang R Rana:2, Supriya D Malhotra:3
1:Department Of Pharmacology, Smt. NHLMMC Ahmedabad, India, 2nd year Post Graduate Student/Resident doctor, India, 2:Assistant professor, Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, India, 3:Professor and Head, Department of Pharmacology, Smt. NHL Municipal Medical College, Ahmedabad, India

NOX1/NADPH oxidase promotes liver injury through dysfunction of sinusoidal endothelium in nonalcoholic fatty liver disease

[Speaker] Misaki Matsumoto:1
[Co-author] Jia Zhang:1, Xueqing Zhang:1, Chihiro Yabe-Nishimura:1
1:Department of Pharmacology, Kyoto Prefectural University of Medicine, Japan

Modulation of DDAH/ADMA/NOS pathway in pancreatic β-cells under diabetic condition

[Speaker] Yukiko K. Kaneko:1
[Co-author] Misaki Sano:1, Ami Morioka:1, Masato Nojiri:1, Nahoko Kasahara:1, Tomohisa Ishikawa:1
1:Department of Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Japan

The Effects of Astragaloside IV on Kidney in Streptozotocin (STZ)-Induced Diabetic Rats

[Speaker] Fan Yu Yan:1
[Co-author] Li Ping:2, Liu Qing Shan:3, Liu Yan Qing:1, Sun Yong Xin:4
1:The department of Pain, Beijing Tiantan Hospital, Beijing, China, 2:Institute of Clinical Medical Science, China-Japan Friendship Hospital, Beijing, China, 3:Institute of Chinese Minority Traditional Medicine Beijing, China, 4:Department of Rehabilitation the Chinese Medicine University Shenyang, China

Effects of free fatty acids on serotonin 2C receptor and calcium homeostasis in pancreatic beta cells

[Speaker] Yun-Wen Chen:1
1:Department of Pharmacology, National Cheng Kung University, Taiwan

THE PENTOSE PHOSPHATE PATHWAY IS A KEY FACTOR IN HIGH GLUCOSE- ASSOCIATED VASCULAR DAMAGE

[Speaker] Carlos F Sanchez-Ferrer:1,2
[Co-author] Tania Romacho:1, Ines Valencia:1,2, Salvador Moncada:3, Concepcion Peiro:1,2
1:Farmacologia y Terapeutica, Facultad de Medicina, Universidad Autonoma de Madrid, Spain, 2:Instituto de Investigacion Sanitaria IdiPAZ, Spain, 3:Manchester Cancer Centre, University of Manchester, UK

Antihyperglycemic effect of Indorenate on 5-HT receptors

[Speaker] Abigail Silva:1
[Co-author] Enrique Hong:1
1:Farmacobiologia, Centro de Investigacion y de Estudios Avanzados del I. P. N., Mexico

Agents and medicines that reverse age related pseudocapillarization of liver sinusoidal endothelial cells in mice

[Speaker] Nicholas J Hunt:1,2
[Co-author] Glen Lockwood:1,2, Hong Mao:2,3, Alessandra Warren:1, Peter Mccourt:2,3, David Le Couteur:1,2, Victoria Cogger:1,2
1:Biogerontology, ANZAC Research Institute, University of Sydney, Australia, 2:Nutritional Ecology, Charles Perkins Centre, University of Sydney, Australia, 3:Medical Biology, University of Tromso, Norway

Screening of sulfated polysaccharide and sugar-related compounds as the regulator of advanced glycation end-products uptake by macrophage

[Speaker] Takashi Nishinaka:1
[Co-author] Takuro Kobori:1, Yui Yamazaki:1, Shinichi Hamasaki:2, Atsuhiro Kitaura:2, Atsuko Niwa:1, Shuji Mori:3, Masahiro Nishibori:4, Hideo Takahashi:1
1:Department of Pharmacology, Faculty of Medicine, Kindai University, Japan, 2:Department of Anesthesiology, Faculty of Medicine, Kindai University, Japan, 3:School of Pharmacy, Shujitsu University, Japan, 4:Department of Pharmacology, Okayama University, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan

The measurement of temporal changes in plasma glucose concentration and energy consumption with respiratory and metabolism analysis system for animals and continuous glucose monitoring system

[Speaker] Shinichi Ozato:1
[Co-author] Seichi Katayama:1, Naoyuki Hironaka:1, Katsuhide Nishi:1
1:Kumamoto Laboratory, LSI Medience Corporation, Japan

Naphthoquinone pigment, a gift for metabolic diseases

[Speaker] Banghao Zhu:1
1:Pharmacology, Sun Yat-Sen University, China

Long-Term Dietary Nitrite and Nitrate Deficiency Causes Metabolic Syndrome, Endothelial Dysfunction, and Cardiovascular Death in Mice

[Speaker] Masato Tsutsui:1
[Co-author] Mika Kina-Tanada:1,4, Mayuko Sakanashi:1, Toshihiro Matsuzaki:1, Katsuhiko Noguchi:1, Junko Nakasone:1, Hiroaki Shimokawa:2, Yusuke Ohya:3, Akira Arasaki:4
1:Department of Pharmacology, Ryukyu University Graduate School of Medicine, Japan, 2:Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine, Japan, 3:Third Dept Intern Med, Ryukyu University Graduate School of Medicine, Japan, 4:Department of Dental Surgery, Ryukyu University Graduate School of Medicine, Japan

High fat/high dextrose diet induces metabolic syndrome in experimental rat model

[Speaker] Amaya Aleixandre:1
[Co-author] Silvia Moreno-Fernandez:2, Marta Garces-Rimon:3, Francisca Fernandez:2, Gema Vera:4, Uranga-Ocio Jose Antonio:5, Marta Miguel:2
1:Farmacologia, Facultad de Medicina. Universidad Complutense de Madrid, Spain, 2:Instituto de Investigacion en Ciencias de la Alimentacion (CIAL, CSIC-UAM), Madrid, Spain, 3:Biotecnologia Alimentaria, Universidad Francisco de Vitoria, Madrid, Spain, 4:Farmacologia y Nutricion. Facultad de Ciencias de la Salud. Universidad Rey Juan Carlos (URJC), Madrid, Spain, 5:Histologia y Anatomia Patologica, Facultad de Ciencias de la Salud. Universidad Rey Juan Carlos (URJC), Madrid, Spain

PPAR gamma agonist rosiglitazone switches fuel preference to lipids in promoting adaptive thermogenesis under cold exposure

[Speaker] Wei Chen:1
[Co-author] Rong Gao:1,2, Huang Yan:1, Xinni Xie:1, Fangting Dong:2, Lili Wang:1
1:Beijing Institute of Pharmacology and Toxicology, China, 2:National Center of Biomedical Analysis, Beijing, China

Antihyperglycemic effect of Quipazine in rats by 5-HT2 receptor stimulation

[Speaker] Enrique Hong:1
[Co-author] Itzel S De La Rosa:1
1:Farmacobiologia, Centro de Investigacion y de Estudios Avanzados del I. P. N., Mexico

Functional analysis of choline transporter-like proteins in rheumatoid arthritis synovial fibroblasts: A novel molecular target for rheumatoid arthritis

[Speaker] Masato Inazu:1,2
[Co-author] Masayuki Seki:3,4, Tsuyoshi Yamanaka:2, Masato Odawara:3
1:Institute of Medical Science, Tokyo Medical University, Japan, 2:Department of Molecular Preventive Medicine, Tokyo Medical University, Japan, 3:Department of Diabetes, Metabolism, Endocrinology, Rheumatology and Collagen Diseases, Tokyo Medical University, Japan, 4:Sakuragaoka Internal Medicine Clinic, Japan

Dapagliflozin Decrease Fructose-Induced Oxidative Stress Mediated by AGE- MMP9 via a SGLT-2-Dependent Mechanism in the Lens of Type 2 DM Model

[Speaker] Ying-Ying Chen:1
[Co-author] Tsung-Tien Wu:2, Pei-Wen Cheng:3
1:Department of Ophthalmology, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, 2:National Yang-Ming University, Taipei, Taiwan, 3:Department of Medical Education and Research, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan

A limonene-derivative purified from peels of Citrus Sudachi ameliorates lipid and glucose metabolism through upregulating sirt1

[Speaker] Licht Miyamoto:1
[Co-author] Haruna Aihara:1, Wenting Xu:1, Meina Jin:1,2, Yosuke Tomida:1, Naonobu Tanaka:2, Yasumasa Ikeda:3, Toshiaki Tamaki:3, Yoshiki Kashiwada:2, Koichiro Tsuchiya:1
1:Medical Pharmacology, Inst. of Biomedical Sciences, Tokushima University, Japan, 2:Pharmacognosy, Inst. of Biomedical Sciences, Tokushima University, Japan, 3:Pharmacology, Inst. of Biomedical Sciences, Tokushima University, Japan

Comparisons of sodium-glucose cotransporter 2 inhibitors-induced adverse reactions between Japanese and non-Japanese patients: a pooled analysis of randomized controlled trials

[Speaker] Toshiki Hayase:1
[Co-author] Mayu Kobayashi:1, Kaori Ambe:1, Masahiro Tohkin:1
1:Regulatory Science, Graduate School of Pharmaceutical Sciences, Nagoya City University, Japan

Hepatic GIP expression is modified by supplementing high-dose thiamine in obese diabetic rats

[Speaker] Yuka Kohda:1
[Co-author] Akie Maekita:1, Takao Tanaka:1, Hitoshi Matsumura:1
1:Laboratory of Pharmacotherapy, Osaka University of Pharmaceutical Sciences, Japan

TRPV2 channels mediate cell swelling-induced insulin secretion in mouse pancreatic β-cells

[Speaker] Toshiaki Sawatani:1
[Co-author] Yukiko Kaneko:2, Isao Doutsu:2, Ai Ogawa:2, Tomohisa Ishikawa:2
1:Pharmacology, Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, Japan, 2:Pharmacology, School of Pharmaceutical Sciences, University of Shizuoka, Japan

Regulator of G-protein signaling Gbeta5-R7 is a crucial activator of muscarinic M3 receptor-stimulated insulin secretion

[Speaker] Vladlen Z. Slepak:1
[Co-author] Qiang Wang:1, Alexey Pronin:1, Joana Almaca:1, Alejandro Caicedo:1
1:Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, USA

Hypothalamic orexin prevents obesity and non-alcoholic fatty liver disease in mice fed high fat diet

[Speaker] Hiroshi Tsuneki:1
[Co-author] Kanta Kon:1, Shinjiro Takata:1, Takahiro Maeda:1, Chiaki Koshida:1, Tsutomu Wada:1, Toshiyasu Sasaoka:1
1:Department of Clinical Pharmacology, University of Toyama, Japan

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