Sessions

BENEFICAL EFFECTS OF BARDOXOLONE METHYL, A NRF2 ACTIVATOR, ON ACETAMINOPHEN-INDUCED ACUTE NEPHROTOXICITY IN RATS

[Speaker] Emine Kadioglu:1
[Co-author] Yasemin Teksen:2, Fikriye Y. Ozatik:2, Orhan Ozatik:3, Zeynep Bayat:4
1:Emergency, Dumlupinar University Faculty of Medicine, Turkey, 2:Pharmacology, Dumlupinar University Faculty of Medicine, Turkey, 3:Histology and Embyrology, Dumlupinar University Faculty of Medicine, Turkey, 4:Biology, Dumlupinar University Art and Science Faculty, Turkey

PROTECTIVE EFFECT OF HYDROGEN SULFIDE AGAINST ACETAMINOPHEN-INDUCED ACUTE NEPHROTOXICITY IN RATS

[Speaker] Fikriye Y Ozatik:1
[Co-author] Yasemin Teksen:1, Emine Kadioglu:2, Orhan Ozatik:3, Zeynep Bayat:4
1:Pharmacology, Dumlupinar University Faculty of Medicine, Turkey, 2:Emergency Medicine, Dumlupinar University Faculty of Medicine, Turkey, 3:Histology and Embrylogy, Dumlupinar University Faculty of Medicine, Turkey, 4:Biology, Dumlupinar University Art and Science Faculty, Turkey

Incidence, mortality and risk factors of drug-induced acute kidney injury: A multi-center study in China

[Speaker] Chen Liu:1
[Co-author] Suying Yan:1, Yuqin Wang:1, Li Yang:2, Qiang Jia:3, Dechun Jiang:1, Yangxin Zhang:1, Xiaohui Cui:1
1:Department of Pharmacy, Xuanwu Hospital, Capital Medical University, China, 2:Department of Nephrology, Peking University First Hospital, China, 3:Department of Nephrology, Xuanwu Hospital, Capital Medical University, China

Dietary Hydroxycinnamates and Resveratrol Reduce Oxidant Injury in Renal Cells

[Speaker] Prabal K Chatterjee:1
[Co-author] Benjamin Elisha-Lambert:1, Ananth S Pannala:1
1:School of Pharmacy & Biomolecular Sciences, University of Brighton, UK

Evaluation of the effect of a bioactive natural product in a mouse model of acute renal failure

[Speaker] Keita Shibata:1
[Co-author] Shohei Kinoshita:1, Terumasa Hashimoto:1, Keiji Hasumi:2, Kazuo Honda:1, Koji Nobe:1
1:Division of Pharmacology, Department of Pharmacology, Toxicology and Therapeutics, Showa University School of Pharmacy, Japan, 2:Department of Applied Biological Science, Tokyo University of Agriculture and Technology, Japan

Carbon monoxide reduces ER stress through suppression of Fyn in acute kidney injury

[Speaker] Eun-Seon Park:1
[Co-author] Md Jamal Uddin:1, Hunjoo Ha:1
1:Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Korea

The Antimicrobial Peptide Cathelicidin protects against ischemia reperfusion-induced acute kidney injury

[Speaker] Li-Long Pan:1
[Co-author] Wenjie Liang:1, Xin Fang:1, Birgitta Agerberth:2, Jia Sun:1
1:Laboratory of Immunopharmacology, School of Medicine, Jiangnan University, China, 2:Department of Laboratory Medicine, Karolinska Institutet, Sweden

Association between urinary vanin-1 and decrease in kidney function in hypertensive patients

[Speaker] Keiko Hosohata:1
[Co-author] Hiroyuki Matsuoka:2, Keiko Hasebe:3, Kazunori Iwanaga:1, Etsuko Kumagai:3
1:Education and Research Center for Clinical Pharmacy, Osaka University of Pharmaceutical Sciences, Japan, 2:Iida Regional Public Health Center, Japan, 3:Department of Nephroogy, Kenwakai Hospital, Japan

Effects of the selective chymase inhibitor, TEI-F00806, on intrarenal renin-angiotensin system in salt-treated angiotensin I-infused hypertensive mice

[Speaker] Akira Nishiyama:1
[Co-author] Yoshihide Fujisawa:2, Daisuke Nakano:1, Hirofumi Hitomi:1, Tuba M Ansary:1
1:Department of Pharmacology, Kagawa University Medical School, Japan, 2:Life Science Research Center, Kagawa University Medical School, Japan

NEPHROPROTECTIVE POTENTIAL OF GREEN TEA EXTRACT IN EXPERIMENTAL INDUCED KIDNEY DYSFUNCTION

[Speaker] S L Harikumar:1
[Co-author] M. Jothi:1, Hardeep Kaur:1, Gurfateh Singh:1
1:UNIVERSITY SCHOOL OF PHARMACEUTICAL SCIENCES, RAYAT BAHRA UNIVERSITY SAHARUAN SAS NAGAR PUNJAB 140104 INDIA

Histone deacetylases 2 in steroid resistant childhood nephrotic syndrome

[Speaker] Harshit Singh:1
[Co-author] Narayan Prasad:2, Saurabh Chaturvedi:1, Vikas Agarwal:1, Kritika Singh:1
1:Clinical Immunology, Sanjay Gandhi Post Graduate Institute of medical Sciences, India, 2:Nephrology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, India

The role of HIF-1 in the development of renal fibrosis in mouse UUO model with special reference to HIF-1 dependent gene expression

[Speaker] Kazuya Kabei:1,2
[Co-author] Yu Tateishi:3, Mayuko Osada-Oka:4, Masakazu Nozaki:1, Masayuki Shiota:5, Masako Tanaka:6, Shuhei Tomita:7, Katsuyuki Miura:1
1:Department of Applied Pharmacology and Therapeutics, Osaka City University Graduate School of Medicine, Japan, 2:Dept Urol, Osaka City University Grad Sch Med, Japan, 3:Dept Nephrol, Ishikiri Seiki Hosp, Japan, 4:Food Hyg Environ Health, Div Appl Life Env Sci, Grad Sch Life Environ Sci, Kyoto Prefectural Univ, Japan, 5:Dept Res Support Platform, Osaka City Univ Grad Sch Med, Japan, 6:Dept Life Sci Med BioSci, Sch Sci Eng, Waseda Univ, Japan, 7:Deprt Pharmacol, Osaka City Univ Grad Sch Med, Japan

Relationship between renal injury and vascular function in rats exposed to renal ischemia/reperfusion

[Speaker] Keisuke Nakagawa:1
[Co-author] Masaya Kanada:1, Masahide Donouchi:1, Ryosuke Tanaka:1, Mamoru Ohkita:1, Yasuo Matsumura:1
1:Laboratory of Pathological and Molecular Pharmacology, Osaka University of Pharmaceutical Sciences, Japan

Relationship between autophagy and acute rejection after kidney transplant

[Speaker] Rao Fu:1
[Co-author] Soichiro Tajima:2, Kimitaka Suetsugu:1,2, Nanae Yamamoto:2, Yasuhiro Okabe:3, Satohiro Masuda:1,2
1:Department of Clinical Pharmacology and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyushu University, Japan, 2:Department of Pharmacy, Kyushu University Hospital, Japan, 3:Department of Surgery and Oncology, Graduate School of Medical Sciences, Kyushu University, Japan

Correlation between T cell subsets and acute graft rejection in tacrolimus-based therapy kidney transplant patients

[Speaker] Suthida Boonsom:1
[Co-author] Suda Vannaprasaht:1, Wichittra Tassaneeyakul:1, Surasakdi Wongratanacheewin:2, Cholatip Pongskul:3, Sirirat Anutrakulchai:3, Chitranon Chan-On:3
1:Department of Pharmacology, Khon Kaen University, Thailand, 2:Department of Microbiology, Khon Kaen University, Thailand, 3:Department of Medicine, Khon Kaen University, Thailand

Effect of Nanocurcumin and Curcumin on Cisplatin-Induced Acute Kidney Failure

[Speaker] Bashar A. W. Pandhita:1
[Co-author] Nielda K. Sumbung:1, Deliana N. I. Rahmi:1, Bernardino M. Waworuntu:1, Melva Louisa:1, Vivian Soetikno:1
1:Pharmacology and Therapeutics, Faculty of Medicine, University of Indonesia, Indonesia

Mild electrical stimulation and heat shock suppress renal pathology in adriamycin-induced nephrotic syndrome model

[Speaker] Keisuke Teramoto:1,2
[Co-author] Kohei Omachi:1,2, Tsubasa Yokota:1, Misato Kamura:1,2, Yu Tsurekawa:1,2, Shota Kaseda:1,2, Haruka Kojima:1, Maryann Suico:1, Tsuyoshi Shuto:1, Hirofumi Kai:1
1:Molecular medicine, Kumamoto University, Japan, 2:HIGO program, Kumamoto University, Japan

MAGI-2 plays a crucial role in homeostasis of the slit diaphragm in kidney podocytes

[Speaker] Naritoshi Shirata:1,2
[Co-author] Motoko Yanagita:2,3, Katsuhiko Nishimori:4, Katsuhiko Asanuma:2,5
1:Mitsubishi Tanabe Pharma Corporation, Japan, 2:Medical Innovation Center, TMK project, Graduate School of Medicine, Kyoto University, Japan, 3:Department of Nephrology, Kyoto University Graduate School of Medicine, Japan, 4:Department of Molecular and Cell Biology, The Laboratory of Animal Breeding and Genetics, Graduate School of Agricultural Science, Tohoku University, Japan, 5:Department of Nephrology, Chiba University Graduate School of Medicine, Japan

ADAMTS1 induces renal inflammation and fibrosis via renin-angiotensin system

[Speaker] Hiroe Toba:1
[Co-author] Yusuke Watanabe:1, Naseratun Nessa:1, Takami Saito:1, Ryoki Kawashima:1, Shiho Sakaue:1, Miyuki Kobara:1, Tetsuo Nakata:1
1:Department of Clinical Pharmacology, Division of Pathological Sciences, Kyoto Pharmaceutical University, Japan

Inhibitory role of Nfe2l2 (Nrf2) in Tgf-beta1-Smad signaling through Smad7 elevation in mouse mesangial MES-13 cell

[Speaker] Seung-Ki Kim:1
[Co-author] Minkyun Song:1, In-Geun Ryoo:1, Jin-Myung Kim:1, Sang-Hwan Lee:1, Mi-Kyoung Kwak:1
1:College of Pharmacy, The Catholic University of Korea, Korea

Evaluation of cardiovascular drugs in post renal transplant patients

[Speaker] Shouvik Choudhury:1
[Co-author] Suparna Chatterjee:2, Arpita Ray Chaudhury:3
1:Pharmacology, post graduate trainee, IPGME&R, Kolkata, India, 2:Dept. of Pharmacology, IPGME&R, Kolkata, India, 3:Dept of Nephrology, IPGME&R, Kolkata, India

Treatment with the SGLT2 inhibitor luseogliflozin attenuated renal capillary injury and fibrosis by VEGF after renal ischemia/reperfusion injury in mice

[Speaker] Daisuke Nakano:1
[Co-author] Yifan Zhang:1, Akira Nishiyama:1
1:Department of Pharmacology, Kagawa University, Japan

SJB-003-085, a newly-synthesized Src kinase inhibitor, attenuates the progression of renal interstitial fibrosis

[Speaker] Debra Dorotea:1
[Co-author] Gayoung Lee:1, Hunjoo Ha:1
1:Graduate School of Pharmaceutical Sciences, College of Pharmacy, Ewha Womans University, Seoul, Korea

Heterogeneity and clinical relevance of tertiary lymphoid tissues in murine and human kidney

[Speaker] Yuki Sato:1,2
[Co-author] Peter Boor:3, Jurgen Floege:4, Motoko Yanagita:2
1:Medical Innovation Center TMK Project, Graduate School of Medicine, Kyoto University, Japan, 2:Department of Nephrology, Graduate School of Medicine, Kyoto University, Japan, 3:Institute of Pathology, RWTH University of Aachen, Germany, 4:Department of Nephrology, RWTH University of Aachen, Germany

Impairment of Calcium-dependent inactivation of TRPC6 Mediated by Calmodulin Underlies Renal Channelopathy

[Speaker] Onur K Polat:1
[Co-author] Masayuki X Mori:1, Masatoshi Uno:2, Hidehito Tochio:2, Yasuo Mori:1
1:Graduate School of Engineering, Department of Synthetic and Biological Chemistry, Japan, 2:Kyoto University, Graduate School of Science, Department of Biophysics, Japan

Effects of yohimbine against lipopolysaccharide-induced acute kidney injury in rats

[Speaker] Takaomi Shimokawa:1
[Co-author] Kozo Yoneda:1
1:Laboratory of Clinical Pharmacology, Faculty of Pharmacy, Osaka Ohtani University, Japan

Assessment of the effects of antidepressants on contractile function of guinea pig urinary bladder and urethra

[Speaker] Keisuke Obara:1
[Co-author] Hiroko Suzuki:1, Satomi Miyatani:1, Satoko Imanaka:1, Hiroka Fukuhara:1, Fumiko Yamaki:1, Takashi Yoshio:2, Yoshio Tanaka:1
1:Department of Chemical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Japan, 2:Department of Clinical Pharmacology, Faculty of Pharmaceutical Sciences, Toho University, Japan

Effect of single dose imipramine on urethral opening pressure - a randomized, placebo-controlled, double-blind crossover study in healthy women

[Speaker] Jonatan Kornholt:1
[Co-author] David P Sonne:1, Troels Riis:1, Jesper Sonne:1, Klarskov Niels:2
1:Department of Clinical Pharmacology, University Hospital Bispebjerg and Frederiksberg, Denmark, 2:Herlev and Gentofte Hospital, Department of Gynecology and Obstetrics, Denmark

Pharmacology of the porcine ureter - the effect of age

[Speaker] Iris Lim:1
[Co-author] Russ Chess-Williams:1, Donna Sellers:1
1:Centre for Urology Research, Bond University, Gold Coast, Australia

The role of rho-kinase in phenylephrine and 5-HT-induced smooth muscle contractions in the porcine ureter

[Speaker] Iris Lim:1
[Co-author] Russ Chess-Williams:1, Donna Sellers:1
1:Centre for Urology Researh, Bond University, Australia

Oxytocin as a pharmacological target for benign prostatic hyperplasia

[Speaker] Betty Exintaris:1
[Co-author] Sophie Lee:2, Johanna Hammar:2, Jenna Kraska:2, Melissa Papargiris:2, Michael Whittaker:3, Gail Risbridger:2, Stuart Ellem:2, Ralf Middendorff:4
1:Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Australia, 2:Department of Anatomy and Developmental Biology, Monash Biomedicine Discovery Institute, Monash University, Australia, 3:ARC Centre of Excellence in Convergent Bio-Nano Science & Technology, Monash Institute of Pharmaceutical Sciences, Australia, 4:Institute of Anatomy and Cell Biology, Justus Liebig University, Giessen, Germany

Synergistic effects of 15-deoxy-Δ12, 14-prostaglandin J2 and anticancer agents on renal cell carcinomas

[Speaker] Tomonari Fujita:1
[Co-author] Yui Asanoma:1, Wakana Shirai:1, Ena Hashimoto:1, Tomoki Echigo:1, Yuri Yoneda:2, Hiroaki Kumagai:2, Hiromi Koma:2, Yasuhiro Yamamoto:2, Tatsurou Yagami:2
1:Hyogo Prefectural Kobe High School, Japan, 2:Himeji Dokkyo University, Japan

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