Sessions

CDK9 Inhibitor FIT-039 Suppresses Viral Oncogenes E6 and E7 and Has Therapeutic Effect on HPV-Induced Neoplasia

[Speaker] Masahiko Ajiro:1
[Co-author] Hiroyuki Sakai:2, Hiroshi Onogi:3, Takashi Nomura:4, Kenji Kabashima:4, Masatoshi Hagiwara:1,5
1:Department of Drug Discovery Medicine, Kyoto University Graduate School of Medicine, Japan, 2:Laboratory of Tumor Viruses, Institute for Frontier Life and Medical Sciences, Kyoto University, Japan, 3:KinoPharma Inc., Japan, 4:Department of Dermatology, Kyoto University Graduate School of Medicine, Japan, 5:Department of Anatomy and Developmental Biology, Kyoto University Graduate School of Medicine, Japan

PTK7 promotes proliferation and invasion of esophageal squamous cell carcinoma cells

[Speaker] Seung-Taek Lee:1
[Co-author] Won-Sik Shin:1
1:Department of Biochmistry, Yonsei University, Korea

Targeting Androgen Receptor and TRAIL: A Novel Treatment Paradigm for Breast Cancer

[Speaker] Yaping Tu:1
[Co-author] Yan Xie:1, Peter W. Abel:1, Taotao Wei:2, Xu Luo:3
1:Pharmacology, Creighton University School of Medicine, USA, 2:National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, China, 3:University of Nebraska Medical Center, USA

Whole-organ profiling of drug resistance in cancer

[Speaker] Shimpei I Kubota:1
[Co-author] Kei Takahashi:1, Jun Nishida:1, Shogo Ehata:1, Kazuki Tainaka:3, Ueda R Hiroki:2, Kohei Miyazono:1
1:Department of Molecular Pathology, The University of Tokyo, Japan, 2:Department of Systems Pharmacology, The University of Tokyo, Japan, 3:Brain Research Institute, Niigata University, Japan

Dose rationale and design of a first-time-in-children protocol for the evaluation of MYCN inhibition in neuroblastoma

[Speaker] Oscar Della Pasqua:1
[Co-author] Sean Oosterholt:1, Anna Lisa Scardovi:2, Roberto Tonelli:3
1:Clinical Pharmacology & Therapeutics Group, School of Pharmacy, University College London, UK, 2:Biogenera Spa, Italy, 3:Department of Pharmacy and Biotechnology, University of Bologna, Italy

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