Sessions

Communication between astrocyte and metastasized cancer cell focused on changes of cellular metabolism

[Speaker] Hiromi Sato:1
[Co-author] Ayaka Shimizu:1, Miaki Uzu:2, Koichi Ueno:3, Akihiro Hisaka:1
1:Laboratory of Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University, Japan, 2:Division of Cancer Pathophysiology, National Cancer Center Research Institute, Japan, 3:Center for Preventive Medical Science, Chiba University, Japan

Orthogonal Arrays of Particles alter cytoskeleton and cell invasion dynamics in GBM and glioma cells

[Speaker] Grazia P. Nicchia:1,2
[Co-author] Laura Simone:1,3, Maria G. Mola:1, Francesco Pisani:1, Concetta D. Gargano:1, Antonio Frigeri:2,4, Maria Svelto:1
1:Dept of Bioscience, Biotechnology and Biopharmaceutics, University of Bari “Aldo Moro”, Italy, 2:Department of Neuroscience, Albert Einstein College of Medicine, Yeshiva University, New York, Bronx, NY, USA, 3:IRCCS Casa Sollievo della Sofferenza, ISBReMIT- Institute for Stem Cell Biology, Regenerative Medicine and Innovative Therapies, San Giovanni Rotondo (FG), Italy, 4:Dept of Basic Medical Science, Neuroscience and SO, University of Bari Aldo Moro, Italy

Pharmacological activities of sesquiterpene lactone trilobolide and its conjugates as a promising compounds for anticancer and immunomodulatory therapies

[Speaker] Eva Kmonickova:1,2
[Co-author] Silvie Rimpelova:2,3, Michal Jurasek:3, Petr Dzubak:4, David Sedlak:5, Zdenek Zidek:1, Juraj Harmatha:6, Pavel Drasar:3
1:Dept. Pharmacology, The Czech Academy of Sciences, Institute of Experimental Medicine, Czech Republic, 2:Dept. Pharmacology, Faculty of Medicine in Pilsen, Charles University, Czech Republic, 3:Dept. Chemistry of Natural Compounds, Faculty of Food and Biochemical Technology, University of Chemistry and Technology Prague, Czech Republic, 4:Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University and University Hospital in Olomouc, Czech Republic, 5:CZ-OPENSCREEN: National Infrastructure for Chemical Biology, Institute of Molecular Genetics AS CR Prague, Czech Republic, 6:The Czech Academy of Sciences, Institute of Organic Chemistry and Biochemistry, Czech Republic

Exploiting ABCG2 Inhibition to Improve Cancer Therapy

[Speaker] Yu Fukuda:1
[Co-author] Alice Allcock:1, Juwina Wijaya:1, Tomoka Gose:1, Wenwei Lin:2, Taosheng Chen:2, John D. Schuetz:1
1:Pharmaceutical Sciences, St. Jude Children's Research Hospital, USA, 2:Chemical Biology and Therapeutics, St. Jude Children's Research Hospital, USA

DRUGGING THE ELUSIVE RAS ONCOPROTEIN WITH SEMISYNTHETIC ANDROGRAPHOLIDE DERIVATIVES

[Speaker] Johnson Stanslas:1
[Co-author] Shun Ying Quah:1, Michelle S Tan:1, Yuan Han Teh:1, Pran K Deb:2, Sreenivasa R Sagineedu:3
1:Medicine, Universiti Putra Malaysia, Malaysia, 2:Faculty of Pharmacy, Philadelphia University, Jordan, 3:Department of Pharmaceutical Chemistry, International Medical University, Malaysia

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