Protective Role of Myelocytic Nitric Oxide Synthases in Hypoxic Pulmonary Hypertension in Mice

[Speaker] Masato Tsutsui:1
[Co-author] Takaaki Ogoshi:2, Takashi Kido:2, Sohsuke Yamada:3, Ke-Yong Wang:4, Yumiko Toyohira:5, Hiroaki Shimokawa:6, Nobuyuki Yanagihara:5, Kazuhiro Yatera:2, Hiroshi Mukae:7
1:Department of Pharmacology, Ryukyu Univ. Graduate School of Medicine, Japan, 2:Department of Respiratory Medicine, Univ. Occup. & Environ. Health, Japan, 3:Department of Pathology, Univ. Occup. & Environ. Health, Japan, 4:Shared-Use Research Center, Univ. Occup. & Environ. Health, Japan, 5:Department of Pharmacology, Univ. Occup. & Environ. Health, Japan, 6:Department of Cardiovascular Medicine, Tohoku Univ. Graduate School of Medicine, Japan, 7:Department of Respiratory Disease, Nagasaki Univ. Grad. Sch. Biomed. Sci., Japan

EP4 agonists have reduced bronchodilation activity in patients with Group III pulmonary hypertension

[Speaker] Xavier Norel:1
[Co-author] Chabha Benyahia:1, Gulsev Ozen:2, Herve Mal:4, Adam M. Silverstein:3, Richard Bayles:1, Andrew C. Nelsen:3, Yves Castier:4, Lucie H. Clapp:5, Dan Longrois:1,4
1:INSERM, UMR-S 1148, CHU X. Bichat, Paris, France; - Paris 13 University, USPC, 93430 Villetaneuse, France, 2:Faculty of Pharmacy, Department of Pharmacology, Istanbul University, Istanbul 34116, Turkey, 3:United Therapeutics, Research Triangle Park, NC 27709, USA, 4:Hopital Bichat-Claude Bernard, AP-HP, Paris Diderot University, USPC, 75018 Paris, France, 5:Department of Medicine, University College London, London WC1E 6JF, UK

Protective Effects of Receptor-interacting Protein 2 Gene Silencing in Cigarette Smoke-induced Acute Lung Injury

[Speaker] Wupeng Liao:1
[Co-author] Jinrui Dong:1, Lay Hong Tan:1, Amy Yong:2, Wen Yan Peh:1, W. S. Fred Wong:1,3,4
1:Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore, 2:Department of Pharmacology and Therapeutics, Faculty of Life Sciences and Medicine, King's College London, UK, 3:Immunology Program, Life Science Institute, National University of Singapore, Singapore, 4:Singapore-HUJ Alliance for Research and Enterprise, National University of Singapore, Singapore

Cigarette Smoke Upregulates PDE3 and PDE4 to Decrease cAMP in Airway Cells

[Speaker] Martina Schmidt:1,2
[Co-author] Haoxiao Zuo:1,2, Viacheslav Nikolaev:3
1:Molecular Pharmacology, University Groningen, the Netherlands, 2:University Medical Center Groningen, Groningen Research Institute for Asthma and COPD, GRIAC, Groningen, the Netherlands, 3:Institute of Experimental Cardiovascular Research, University Medical Centre Hamburg-Eppendorf, 20246 Hamburg, Germany

Development of carrier-free, inhalable powder formulation of siRNA therapeutics for the treatment of respiratory diseases

[Speaker] Jenny KW Lam:1
[Co-author] Wanling Liang:1, Michael Yt Chow:1
1:Pharmacology and Pharmacy, The University of Hong Kong, Hong Kong

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