Adverse Drug Reactions Reporting in a Teaching Hospital in Taiwan

[Speaker] Yuhong Lin:1
[Co-author] Hsinhui Huang:1
1:Pharmacy, Kaohsiung Veterans General Hospital Tainan Branch, Taiwan

Background: An adverse drug reaction (ADR) could be defined as any unintended, unexpected response attributed to taking medicines. The severity of ADR may vary greatly from person to person. The most severe situation can be a life-threatening event. In order to make healthcare professionals become aware of the importance of ADR, we do data analysis from our hospital.
Methods: It was a retrospective study in 2016. Assessment of ADRs contains age, gender, occurring sources, sources of ADRs reporting, Classification of ADRs, and Naranjo score calculating by Naranjo Adverse Drug Reaction Probability Scale. In addition, we do a sub-analysis regarding Anatomical Therapeutic Chemical (ATC) classification of suspected drugs and Adverse Effects.
Results: The investigation included eighty-nine ADRs reported. The average age was 67.6 year. Most of ADRs reported were occurring in outpatient department (87.6%). Majority of all ADRs reported were females (55.1%). Also, the major Naranjo scores of all ADRs reported ranged from 1 to 4 points (92.1%), which represents a possible correlation between ADRs reported and suspected drugs. According to ATC classification system, the major classification of suspected drugs were Sensory organs (32.6%) and Dermatologic Effects (37.1%) were the major adverse effects.
Conclusions: ADR reporting certainly is still a very important process for healthcare professionals. For that reason, we have put ADRs reporting information into our medical computer system. By medical computer system, it can remind clinical physician to consider prescribing medication. There is always a potential risk while taking medicines. Consequently, it is truly a best way to improve medication safety by spontaneous reporting of ADRs by healthcare professionals for all patients.

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