The Construction of Cell-based Reporter Model for anti-Cerebral Ischemia

[Speaker] Rui Tan:1
1:School of Medical, Southwest Jiaotong University, China

Ischemic cerebrovascular disease (ICVD) is a major cause for death and long-term disability in worldwide , and there is no effective drugs currently. Actually, traditional Chinese medicine (TCM) has a long history in ICVD treatment and there are a variety of compounds , active fractions or compound formulations proved effective to the prevention and treatment of ICVD. However, the exact active compounds and mechanisms are not yet fully understood. Therefore, a simple screeing model for ICVD is necessary fordiscovering active compounds and lead compounds from TCM. In our research, a cell-based reporter model with 3promoters was constructed to screen the potential anti-ICVD drugs systematically and effectivel.
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