Program

PO1-13-1

Integrating Traditional Diet and Herbal Medicine in Research and Clinical Practice

[Speaker] Badiaa Lyoussi:1
1:University Sidi Mohamed Ben Abdallah, Fez, Laboratory Physiology-Pharmacology & Environmental Health, Morocco

Parallel to the observed increasing interest in therapies based on traditional medical system, there is a similar trend in research activities dealing with the safety and efficacy of diets and medicinal herbs throughout the Mediterranean region. These therapies have been utilized by people who have faith in herbalists, spiritual healers, or even homeopaths. These people are the first choice for problems such as diabetes, obesity, infertility, impotence, psychosomatic troubles, and many other diseases. The modern use of herbal medicines has historical roots in Greco-Arab and Islamic medicine, which was developed in the golden age (seventh to fifteenth century) of the Islamic civilization. This medical system has great influence on Europe where it formed the roots from which modern Western medicine arose.
Pharmacologists are always in the search of new drugs or treatment options with better efficacy and safety profile. One way to achieve this goal is to search for chemicals with selective effect at the site of desired action while an alternate approach could be searching for combination of activities with synergisitc and/or side effects neutralzing potential in botanicals. There is a revival of interest in the use of medicinal plants in the form of standardized extracts partly due to high cost involved in the development of patentable chemical drugs.
This presentation presents a systematic review on Greco-Arab and Islamic herbal medicine and a state of the art description of risks and benefits of their use in the treatment of inflammation and diabetes. Our results suggest that the traditional uses of plants extracts, bee products as anti-inflammatory remedy may be mediated by their significant antioxidant capacity, inhibition of pro-inflammatory cytokines secretion IL-1, IL-6 and TNF-α concomitant with enhancement of anti-inflammatory cytokines secretion IL-10 as well as their mRNA expression in human THP-1-derived macrophages.
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